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SYRINGES Conventional insulin administration involves
subcutaneous injection with syringes marked in insulin units. There may
be differences in the way units are indicated, depending on the size of
the syringe and the manufacturer. Insulin syringes are manufactured with
0.25-, 0.3-, 0.5-, and 1-ml capacity. Two lengths of needles are
available: short, 8 mm, and long, 12.7 mm. The short needles are not
indicated for the obese patient because of variability of insulin
absorption. Regulations governing the purchase of syringes vary greatly
from one state to another.
Syringes must never be shared with another person because of the risk of
acquiring a blood-borne viral infection (e.g., acquired immune
deficiency syndrome or hepatitis). Travelers should be aware that
insulin is available in a strength of U-40 outside of the U.S. To avoid
dosing errors, syringes that match the concentration of U-40 insulin
must be used. |
| Disposal Regulations in some states require
the destruction of used insulin syringes and needles. Recapping, bending
or breaking a needle increases the risk of needle-stick injury. Unless
the syringe will be reused, it should be placed in a puncture-resistant
disposal container or needle-clipping device, which retains the clipped
needle in an inaccessible compartment. In areas with container-recycling
programs, placement of containers of used syringes, needles, and lancets
with materials to be recycled is prohibited. Local trash-disposal
authorities should be consulted to determine the appropriate disposition
of such containers. The likelihood of reuse of a syringe by another
person is decreased if the plunger is separated from the barrel at the
time of disposal.
Disposable insulin pens are available that contain a limited capacity
of insulin (e.g., 150 units). Users select the dose, inject the insulin
and then discard the needle according to local regulations. After all of
the insulin has been used, the pen device can be discarded in the
garbage can with regular trash.
Syringe reuse Manufacturers of disposable syringes recommend that
they be used only once, because the sterility of a reused syringe cannot
be guaranteed. However, some individuals prefer to reuse a syringe until
its needle becomes dull. Most insulin preparations have bacteriostatic
additives that inhibit growth of bacteria commonly found on the skin.
For many patients, it appears both safe and practical for the syringe to
be reused if the patient so desires. The syringe should be discarded
when the needle becomes dull, has been bent, or has come into contact
with any surface other than the skin; if reuse is planned, the needle
must be recapped after each use. Syringe reuse may carry an increased
risk of infection for some individuals. Patients with poor personal
hygiene, an acute concurrent illness, open wounds on the hands, or
decreased resistance to infection for any reason should not reuse a
syringe. Patients reusing a syringe should periodically inspect the skin
around an injection site for unusual redness or signs of infection.
Individuals should consult their physicians before initiating the
practice of syringe reuse and whenever injection-site infection is
suspected. Before syringe reuse is considered, it should be determined
that the patient is capable of safely recapping a syringe. Proper
recapping requires adequate vision, manual dexterity, and no obvious
tremor. The patient should be instructed in a recapping technique that
supports the syringe in the hand and replaces the cap with a straight
motion of the thumb and forefinger. The technique of guiding both the
needle and cap to meet in midair should be discouraged, because this
frequently results in needle-stick injury. The syringe being reused may
be stored at room temperature. The potential benefits or risks, if any,
of refrigerating the syringe in use or of using alcohol to cleanse the
needle of a syringe are unknown. Cleansing the needle with alcohol may
not be desirable, because it may remove the silicon coating that makes
for less painful skin puncture.
SYRINGE ALTERNATIVES Insulin can be given with jet injectors that
inject insulin as a fine stream into the skin. These injectors offer an
advantage for patients unable to use syringes or those with needle
phobias. A potential advantage may be a more rapid absorption of
short-acting insulin. However, the initial cost of these injectors is
relatively high, and they may traumatize the skin. They should not be
viewed as a routine option for use in patients with diabetes. Several
pen-like devices and insulin- containing cartridges are available that
deliver insulin subcutaneously through a needle. In selected patients
(e.g., those who are visually and/or neurologically impaired and those
using multiple daily injection regimens), these devices may improve
accuracy of insulin administration and/or be more convenient.
This information and more information can be found at The American
Diabetes Association http://diabetes.org/diabetescare/supplement198/s72.htm |